Thermo Fisher Scientific BEX1/BEX2 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human BEX1/BEX2 C-terminal region. Suitable for Western blot applications. High concentration liquid form for research use. Predicted reactivity with mouse and rat. Store at 4°C short term, -20°C long term.
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Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BEX1/2 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.38 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735525 |
Product Specific Information
- Positive Control: Synthetic peptide (1:8000)
- Predicted Reactivity: Mouse (100%), Rat (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
BEX1/BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. BEX1/BEX2 functions as a tumor suppressor silenced in human glioma. In breast cancer cells, it modulates apoptosis in response to estrogen and tamoxifen, enhancing the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been identified for this gene.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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