Thermo Fisher Scientific SCCPDH Polyclonal Antibody
Thermo Fisher Scientific SCCPDH Polyclonal Antibody는 인간 SCCPDH 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot에 적합하며 다양한 종에서 교차 반응성을 보입니다. 액상 형태로 제공되며 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 37–230 of Human SCCPDH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549416 |
Product Specific Information
- Recommended positive controls: U87-MG
- Predicted reactivity: Human (99%), Mouse (85%), Rat (87%), Pig (84%), Chimpanzee (98%), Bovine (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family.
The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C. elegans, and maps to human chromosome 1q44.
Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and comprising approximately 8% of the human genome.
It contains about 3,000 genes, and numerous diseases are associated with chromosome 1, including Stickler syndrome, Parkinson’s disease, Gaucher disease, and Usher syndrome.
A breakpoint identified in 1q disrupts the DISC1 gene and is linked to schizophrenia.
Aberrations in chromosome 1 are found in various cancers such as head and neck cancer, malignant melanoma, and multiple myeloma.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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