Thermo Fisher Scientific SCFD1 Polyclonal Antibody
SCFD1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도의 액상 항체로 -20°C 보관이 필요합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SCFD1 (Accession Q8WVM8), corresponding to amino acid residues M532–P582. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851290 |
Product Specific Information
This antibody detects endogenous levels of total SCFD1.
Target Information
The de novo synthesis of pyrimidine nucleotides is essential for mammalian cell proliferation. The SCFD1 gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, linking MAPK activation to de novo pyrimidine biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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