Thermo Fisher Scientific PRKY Polyclonal Antibody
PRKY 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. Western Blot 및 Immunocytochemistry에 사용 가능하며, 고순도 Affinity Chromatography 정제 제품입니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PRKY (Accession O43930), corresponding to amino acid residues K219–F269 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851298 |
Product Specific Information
Antibody detects endogenous levels of total PRKY.
Target Information
A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases.
PRKY (protein kinase, Y-linked) and PRKX (protein kinase, X-linked) are members of the Ser/Thr protein kinase family, both belonging to the subfamily of cAMP-dependent kinases.
Encoded by a gene located near the pseudoautosomal region on chromosome Y, PRKY contains one protein kinase domain that catalyzes ATP-dependent phosphorylation of target proteins.
Functioning similarly to PRKX, PRKY is essential for macrophage differentiation and renal epithelial cell migration.
Defects in PRKY and PRKX genes are associated with sex reversal disorders (XX males and XY females).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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