Thermo Fisher Scientific IRAK-M Monoclonal Antibody (6G9G2)
IRAK-M 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 6G9G2). Western blot, IHC, ICC/IF, Flow Cytometry, ELISA 등에 사용 가능. Human 시료 반응성, Protein G 정제, PBS buffer 및 sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific IRAK-M Monoclonal Antibody (6G9G2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6G9G2 |
| Immunogen | Purified recombinant fragment of human IRAK3 (aa 454–596) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898457 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
IRAK3 (Interleukin-1 Receptor-Associated Kinase 3) is a serine/threonine kinase and a member of the IRAK protein family, essential for Toll/IL-R immune signal transduction. It is primarily expressed in monocytes and macrophages and acts as a negative regulator of Toll-like receptor signaling. IRAK3 mediates key aspects of innate immunity and is implicated in immunocompromised states during sepsis. Mutations in IRAK3 are associated with susceptibility to asthma.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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