Thermo Fisher Scientific SCN1B Polyclonal Antibody
SCN1B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific SCN1B Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SCN1B (Accession Q07699), corresponding to amino acid residues K184–E218 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853485 |
Product Specific Information
Antibody detects endogenous levels of total SCN1B.
Target Information
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They consist of one alpha and two beta subunits. The alpha subunit provides channel activity, while the beta-1 subunit modulates channel inactivation kinetics.
SCN1B encodes the sodium channel beta-1 subunit. Mutations in this gene are associated with generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and cardiac conduction defects. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-104157_SCN1B_Q07699-1_Rabbit_PDP.jpeg)
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