Thermo Fisher Scientific PDCD6 Polyclonal Antibody
PDCD6 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 IHC(파라핀 절편)에 사용 가능. 인간 및 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 4°C 또는 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human PDCD6 (aa 1–191) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913324 |
Product Specific Information
- Positive Control: SK-Br-3 cell lysate, HepG2 cell lysate, rat ovary tissue lysate, human breast carcinoma tissue, human placenta tissue, human stomach carcinoma tissue
- Subcellular Location: Endosome, Endoplasmic reticulum membrane, Nucleus, COPII-coated vesicle membrane, Cytoplasm
Target Information
An increased intracellular Ca²⁺ concentration induces apoptotic cell death. Transiently elevated Ca²⁺ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis. ALG-2 (apoptosis-linked gene 2) is a Ca²⁺-binding protein that participates in regulatory events occurring late in the apoptotic program and where several death signals converge. ALG-2 is expressed in normal brain and to a greater extent in ischemic brain. The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, including Calpain small subunits sorcin and grancalcin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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