Thermo Fisher Scientific SPDYA Polyclonal Antibody
Rabbit polyclonal antibody specific to human SPDYA protein. Validated for ICC/IF applications. Purified by antigen affinity chromatography and supplied in PBS with glycerol. Suitable for research use in cell cycle regulation studies.
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Applications
Tested Dilution
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human SPDYA (Product # RP-104246) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856464 |
Product Specific Information
Immunogen sequence:
CCEEVMAIAP THYIWQRERS VHHSGAVRNY NRDEVQLPRG PSATPVDCSL CGKKRRYVRL GLSSSSS
Target Information
Speedy A (SPDYA), also known as SPDY1, Ringo3, or SPY1, is a 313 amino acid nuclear protein belonging to the speedy/ringo family. It is highly expressed in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver, spleen, and placenta.
Speedy A regulates the G1/S phase transition of the cell cycle by binding to and activating Cdc2 p34, Cdk2, and p27. It also mediates cell survival during DNA damage, indicating a role in maintaining proper cell cycle progression.
Multiple isoforms exist due to alternative splicing. The SPDYA gene is located on human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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