Thermo Fisher Scientific HNF4A Monoclonal Antibody (OTI5A9), TrueMAB
HNF4A 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 최적화됨. 인간 유래 HNF4A(aa 1-315) 항원을 기반으로 제작. 동결건조 형태이며 보존제 없음. 연구용으로 MODY1 관련 연구에 적합.
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Thermo Fisher Scientific HNF4A Monoclonal Antibody (OTI5A9), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5A9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–315 of human HNF4A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Hepatocyte nuclear factor 4 alpha (HNF4A) is an orphan nuclear receptor expressed in the liver, kidney, intestine, and pancreas.
Mutations in HNF4A are associated with maturity-onset diabetes of the young type 1 (MODY1).
HNF4 binds DNA as a homodimer, and alternative splicing can produce up to nine isoforms (HNF4A1–HNF4A9).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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