Thermo Fisher Scientific DOK7 Polyclonal Antibody
DOK7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간 및 마우스 반응성. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DOK7 (Accession Q18PE1), corresponding to amino acid residues P415–T465 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850623 |
Product Specific Information
Antibody detects endogenous levels of total DOK7.
Target Information
The protein encoded by this gene is essential for neuromuscular synaptogenesis. It functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation and clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase.
Mutations in this gene cause familial limb-girdle myasthenia autosomal recessive (congenital myasthenic syndrome type 1B).
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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