Thermo Fisher Scientific Kir1.1 (KCNJ1) Polyclonal Antibody
Kir1.1(KCNJ1) 단백질을 인식하는 염소 유래 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간에 반응하고 마우스 및 랫트에도 예측 반응. 합성 펩타이드 항원으로 제작되어 고특이성 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DQININFVVDAGNEN) corresponding to internal amino acids of KCNJ1 (aa 245–259) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11001741 |
Product Specific Information
- This antibody is predicted to react with mouse and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
Potassium channels are present in most mammalian cells, participating in various physiological responses.
The protein encoded by KCNJ1 is an integral membrane protein and inward-rectifier type potassium channel, activated by internal ATP, and plays a key role in potassium homeostasis.
It allows potassium to flow preferentially into cells rather than out.
Mutations in this gene are linked to antenatal Bartter syndrome, characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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