Thermo Fisher Scientific GPR116 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 10 µg/mL
• 참고: For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

Percent identity with other species by BLAST analysis:

• Human, Gorilla, Gibbon: 100%
• Marmoset: 95%
• Monkey: 90%

Target Information

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, comprise a superfamily of proteins involved in numerous stimulus-response pathways. They translate extracellular signals into intracellular responses via G protein activation and respond to various signaling molecules such as hormones and neurotransmitters.
GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein containing one SEA domain, one GPS domain, and three Ig-like domains. It exists as a disulfide-linked homodimer at the cell surface and has multiple alternatively spliced isoforms. GPR116 is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.