Thermo Fisher Scientific Jagged1 Recombinant Rabbit Monoclonal Antibody (JF96-06)
Jagged1 단백질을 표적으로 하는 재조합 토끼 단일클론 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합함. 높은 특이성과 민감도, 로트 간 일관성, 동물유래 성분 없음, 안정적인 장기 보관 가능.
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- MA532537
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JF96-06 |
| Immunogen | Synthetic peptide within Human Jagged1 aa 1182–1214 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809814 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening of individual clones to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
The Jagged1 protein encoded by JAG1 is the human homolog of the Drosophila jagged protein. It serves as a ligand for the receptor Notch1, the human homolog of the Drosophila notch receptor.
Mutations in Jagged1 cause Alagille syndrome. Jagged1–Notch1 signaling also plays a key role in hematopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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