Thermo Fisher Scientific LDHA Recombinant Rabbit Monoclonal Antibody (23GB6060)
LDHA 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 유세포 분석에 적합합니다. 인간, 마우스, 랫트 시료 반응성이 있으며, HEK293F 시스템에서 발현된 IgG 형 항체입니다. 고순도 친화 크로마토그래피 정제 및 안정적인 PBS/glycerol 저장용액 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB6060 |
| Immunogen | A synthesized peptide derived from human Lactate Dehydrogenase (254–300AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Lactate dehydrogenase (LDH) is an enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+.
In mammals, LDH is encoded by three genes: LDHA (muscle form), LDHB (heart form), and LDHC (testis form).
Human LDHs share 84–89% sequence similarity and 69–75% amino acid identity.
There are five LDH isoenzymes formed by combinations of M and H chains in the tetrameric structure.
LDHA expression is hypoxia inducible and regulated by HIF1α, while LDHB is upregulated in many cancers.
Mutations in LDHA can cause Glycogen Storage Disease 11 (GSD11).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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