Thermo Fisher Scientific ARHGEF2 Monoclonal Antibody (9D4)
ARHGEF2 (GEF-H1) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Monoclonal Antibody (Clone 9D4). Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능하며, 1 mg/mL 농도의 액상 형태로 제공. 세포 골격 재구성과 Rho GTPase 활성 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9D4 |
| Immunogen | Recombinant protein corresponding to C-terminal human GEF H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli acting through G protein-coupled receptors.
GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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