Thermo Fisher Scientific MAP2K1 Monoclonal Antibody (OTI8H1), TrueMAB
MAP2K1(MEK1) 단백질을 인식하는 단클론 항체로, Western blot 및 면역세포염색(ICC/IF)에 적합합니다. 인간, 마우스, 랫드, 개에서 반응하며, 액상형 1 mg/mL 농도로 제공됩니다. 세포 성장 및 신호전달 연구용으로 이상적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:4000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8H1 |
| Immunogen | Full length human recombinant protein of human MAP2K1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by various growth factors, cytokines, membrane depolarization, and calcium influx. MEK1 activation occurs via phosphorylation of serine residues 218 and 222 by Raf1. It plays roles in stress response signaling, apoptosis, and cytokine-induced proliferation. Mutations in MAP2K1 are associated with cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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