Thermo Fisher Scientific MAP2K1 Monoclonal Antibody (OTI7F3), TrueMAB
MAP2K1(MEK1) 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot 및 Immunocytochemistry에 사용 가능. Human, Mouse, Rat, Dog 시료 반응. Affinity chromatography로 정제된 1 mg/mL 액상 제품. -20°C 보관, 연구용 전용.
- 카탈로그번호
- TA506032
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:4000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F3 |
| Immunogen | Full length human recombinant protein of human MAP2K1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase functioning in mitogen-activated protein kinase (MAPK) cascades, which control cell growth and differentiation.
MAP2K1 is activated by various growth factors and cytokines, as well as by membrane-dependent depolarization and calcium influx.
Mek1 is activated by phosphorylation at serine 218 and 222 residues by Raf1. It plays roles in stress response signaling, apoptosis, and cytokine-induced proliferation.
Mutations in the MAP2K1 gene are associated with cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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