Thermo Fisher Scientific BCL11A/CTIP1 (Transcription Factor) Monoclonal Antibody (PCRP-BCL11A-1H3)
인간 BCL11A 전사 인자를 인식하는 단일클론 항체로 다양한 면역분석(ICC/IF, Flow, ELISA, IP 등)에 사용 가능. 비결합형 액상 형태이며 200 µg/mL 농도. Protein A/G로 정제되어 높은 특이성과 재현성을 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/100–500 µg total protein |
| Peptide Array | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-BCL11A-1H3 |
| Immunogen | Recombinant full-length human BCL11A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react in Mouse and Rat.
Target Information
This gene encodes a C2H2-type zinc-finger protein similar to the mouse Bcl11a/Evi9 protein. The mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated and may be involved in lymphoma pathogenesis since translocations associated with B-cell malignancies deregulate its expression. Multiple transcript variants encoding several isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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