Thermo Fisher Scientific NXPH2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NXPH2. Recombinant protein control fragment (Product #RP-96122). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NXPH2,uniProtId:O95156-1,ncbiNodeId:9606,antigenRange:18-99,antigenLength:264,antigenImageFileName:PA5-57047_NXPH2_O95156-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57047_NXPH2_O95156-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644926

Product Specific Information

Immunogen sequence: LFCDSKEVVH ATEGLDWEDK DAPGTLVGNV VHSRIISPLR LFVKQSPVPK PGPMAYADSM ENFWDWLANI TEIQEPLART KR

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 68%.

Target Information

Neurexophilin-1 (also known as NPH1 or NXPH1), Neurexophilin-2 (also known as NPH2 or NXPH2) and Neurexophilin-3 (also known as NPH3 or NXPH3) are members of the Neurexophilin family (Neurexophilin-1-4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis. Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I-alpha (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.