
Thermo Fisher Scientific ME3 Polyclonal Antibody
Rabbit polyclonal antibody against ME3 protein. Validated for WB and IHC-P applications. Detects endogenous 67 kDa protein. High purity (>95%) and antigen affinity purified. Supplied in PBS with 50% glycerol and 0.02% sodium azide.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC-P)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 547–598 of human ME3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553551 |
Product Specific Information
- Detects endogenous protein at approximately 67 kDa.
- Purity >95% by SDS-PAGE.
Target Information
ME3 proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in pathological processes including arthritis, metastasis, and atherosclerosis.
Most MMPs are secreted as inactive proproteins that are activated upon cleavage by extracellular proteinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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