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Thermo Fisher Scientific PRPK Polyclonal Antibody
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Thermo Fisher Scientific PRPK Polyclonal Antibody

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Human PRPK 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.

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마지막 업데이트 2025. 08. 04. 오전 06:33
Thermo Fisher Scientific PA582542 PRPK Polyclonal Antibody 100 ul pk판매 단위 pk ·
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740,000원VAT 포함 814,000원

Thermo Fisher Scientific · Thermo Fisher Scientific PRPK Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P)) 1:20–1:50

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant protein corresponding to Human TP53RK. Recombinant protein control fragment (Product # RP-89811)
Conjugate Unconjugated
Form Liquid
Concentration 0.05 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS, pH 7.2, with 40% glycerol
Contains 0.02% sodium azide
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Wet ice
RRID AB_2789700

Product Specific Information

Immunogen sequence:
AAVIKHRFPK GYRHPALEAR LGRRRTVQEA RALLRCRRAG ISAPVVFFVD YASNCLYMEE IEGSVTVRDY IQSTMETEKT PQGLSNLAKT IGQV

Target Information

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914).
The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:27903914).
TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP.
Atypical protein kinase that phosphorylates Ser-15 of p53/TP53 protein and may therefore participate in its activation (PubMed:11546806).
[UniProt]


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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