Thermo Fisher Scientific Cardiac Troponin T Polyclonal Antibody
심근 트로포닌 T를 인식하는 Thermo Fisher의 Rabbit Polyclonal Antibody로, 인간 시료에 반응하며 IHC(P) 등에 사용 가능. 고순도 항원 친화 크로마토그래피 정제, 안정적 PBS/glycerol buffer 제공, 연구용으로 심근 단백질 발현 및 병태 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:2,500–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TNNT2. Recombinant protein control fragment (Product #RP-91307). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789697 |
Product Specific Information
Immunogen sequence:
EEEENRRKAE DEARKKKALS NMMHFGGYIQ KQAQTERKSG KRQTEREKKK KILAERRKVL AIDHLNEDQL REKAKELWQS IYNLEAEKFD LQEKFKQQKY EINVLRNRIN DNQKVSK
Target Information
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, located on the thin filament of striated muscles. It regulates muscle contraction in response to intracellular calcium ion concentration changes and plays a key role in muscle function and myofibril formation.
In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Expression is influenced by heart failure. Mutations in Cardiac Troponin T are associated with familial hypertrophic and dilated cardiomyopathies. Alternative splicing of the gene produces multiple tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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