Thermo Fisher Scientific PAX2 Polyclonal Antibody
상품 옵션 정보 | ||||||||
---|---|---|---|---|---|---|---|---|
카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
716000 | - | Thermo Fisher Scientific 716000 PAX2 Polyclonal Antibody 100 ug pk | 재고문의 | pk | 604,000원 | - | 664,400원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
Assay-dependent
View 7 publications 7 publications
Immunohistochemistry (IHC)
Assay-dependent
View 63 publications 63 publications
Immunohistochemistry (Paraffin) (IHC (P))
-
View 17 publications 17 publications
Immunohistochemistry (Frozen) (IHC (F))
-
View 6 publications 6 publications
Immunohistochemistry - Free Floating (IHC (Free))
-
View 1 publication 1 publication
Immunocytochemistry (ICC/IF)
-
View 22 publications 22 publications
Flow Cytometry (Flow)
-
View 1 publication 1 publication
ELISA (ELISA)
Assay-dependent
Immunoprecipitation (IP)
Assay-dependent
Miscellaneous PubMed (Misc)
-
View 10 publications 10 publications
Product Specifications
Species Reactivity
Human, Mouse, Sheep, Rat, Xenopus, Zebrafish
Published species
Chicken, Cynomolgus monkey, Dog, Human, Mouse, Rat, Rhesus monkey
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
A GST-Pax-2 fusion protein derived from the C-terminal domain (aa188-385) of the murine Pax-2 protein if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
PAX2,
uniProtId:
P32114-1,
ncbiNodeId:
10090,
antigenRange:
188-385,
antigenLength:
414,
antigenImageFileName:
71-6000_PAX2_P32114-1_Rabbit.svg,
antigenImageFileNamePDP:
71-6000_PAX2_P32114-1_Rabbit_PDP.jpeg,
sortOrder:
2}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2533990
Target Information
The pax genes are a family of transcription factors that are active in specific tissues during early embryonic development. Pax family members possess a DNA-binding domain encoded by the paired box. Because paired domain containing genes encode transcription factors, they are capable of executing a genetic program. Several pax genes have also been associated with developmental mutations including: pax-3, which is associated with Waardenburg syndrome, pax-6, which is associated with Aniridia, and pax-2, which is associated with Wilms tumor. During embryogenesis, Pax-2 is expressed in the developing kidney. In particular, the pax-2 gene is expressed in condensing metanephric mesenchyme and in early epithelial structures derived from mesenchyme; however, pax-2 mRNA and protein levels are rapidly down regulated as the tubular epithelium matures. Although Pax-2 is down regulated during renal epithelium maturation, Pax-2 expression persists in the undifferentiated epithelium of Wilmstumors. Persistent expression of Pax-2 in Wilms
tumors occurs frequently and correlates with the proliferation of poorly differentiated epithelial cells in these tumors. Interestingly, expression of the Wilms` tumor suppresser protein, WT1, coincides with down-regulation of the pax-2 gene; thus, suggesting that WT1 can directly repress pax-2 transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
배송/결제/교환/반품 안내
배송 정보
기본 배송비 |
| 교환/반품 배송비 |
|
---|---|---|---|
착불 배송비 |
| ||
교환/반품 배송비 |
|
결제 및 환불 안내
결제 방법 |
|
---|---|
취소 |
|
반품 |
|
환급 |
|
교환 및 반품 접수
교환 및 반품 접수 기한 |
|
---|---|
교환 및 반품 접수가 가능한 경우 |
|
교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
교환 절차 |
|
---|---|
반품 절차 |
|