Thermo Fisher Scientific BMP2K Monoclonal Antibody (4B7)
BMP2K 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(4B7). Western blot 및 ELISA에 적합하며, 골형성 관련 BMP 신호 연구에 활용 가능. 액상 형태로 제공되며 -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B7 |
| Immunogen | BMP2K (AAH36021, 540 a.a. ~ 650 a.a.) partial recombinant protein with GST tag. MW of GST tag: 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
Sequence of this protein is as follows:
YQQAFFQQQM LAQHQPSQQQ ASPEYLTSPQ EFSPALVSYT SSLPAQVGTI MDSSYSANRS VADKEAIANF TNQKNISNPP DMSGWNPFGE DNFSKLTEEE LLDREFDLLR S
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis, and apoptosis.
A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases.
BMP2K (BMP2 inducible kinase), also known as BIKE, is a 1,161 amino acid nuclear protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family.
It is thought to be involved in osteoblast differentiation and catalyzes the ATP-dependent phosphorylation of bone morphogenic proteins (BMPs), which are essential for proper cartilage and bone formation.
Via its catalytic activity, BMP2K may play a role in signaling pathways that mediate bone growth and cellular differentiation.
Three isoforms of BMP2K exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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