Thermo Fisher Scientific CSNK1A1L Polyclonal Antibody
CSNK1A1L 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 항체이며, 인간 시료에 반응합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human CSNK1A1L (UniProt ID: Q8N752-1, Antigen range: 1–337) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720680 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity is >95% (by SDS-PAGE).
Target Information
CSNK1A1L serine/threonine kinase (CK1-alpha) dynamically associates with the CBM complex upon T cell receptor engagement to participate in cytokine production and lymphocyte proliferation. It promotes phosphorylation and inactivation of CARMA1, governing antigen-receptor-induced NF-kappa-B activation and human lymphoma cell survival. These kinases preferentially utilize acidic proteins such as caseins as substrates and can phosphorylate proteins including CTNNB1, PER1, and PER2. CSNK1A1 also participates in Wnt signaling and may play roles in chromosome segregation during mitosis and cytoskeleton disassembly regulating epithelial cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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