Thermo Fisher Scientific Bestrophin 4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Bestrophin 4. Recombinant protein control fragment (Product #RP-101335). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Bestrophin 4,uniProtId:Q8NFU0-1,ncbiNodeId:9606,antigenRange:252-286,antigenLength:473,antigenImageFileName:PA5-63587_Bestrophin_4_Q8NFU0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63587_Bestrophin_4_Q8NFU0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.06 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638535

Product Specific Information

Immunogen sequence: LVGRQFVEPE AGAAKPQKLL KPGQEPAPAL GDPDM

Highest antigen sequence identity to the following orthologs: Mouse - 39%, Rat - 41%.

Target Information

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3` ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.