Thermo Fisher Scientific IRF4 Recombinant Rabbit Monoclonal Antibody (4Z8K2)
IRF4 단백질을 인식하는 토끼 단클론 항체로, 인간 시료에 반응합니다. IHC(P) 및 ELISA에 사용 가능하며, 재조합 형태로 높은 특이성과 재현성을 제공합니다. Protein A로 정제되었으며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4Z8K2 |
| Immunogen | Recombinant fusion protein corresponding to amino acids 351–451 of human IRF4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.18 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
ERDQTCKLFD TQQFLSELQA FAHHGRSLPR FQVTLCFGEE FPDPQRQRKL ITAHVEPLLA RQLYYFAQQN SGHFLRGYDL PEHISNPEDY HRSIRHSSIQ E
Target Information
The IRF (interferon regulatory factor) family of transcription factors is characterized by a unique tryptophan pentad repeat DNA-binding domain. IRFs regulate interferon expression in response to viral infection and control interferon-inducible genes. IRF4 is lymphocyte-specific and negatively regulates toll-like receptor (TLR) signaling, which is central to innate and adaptive immune activation. A chromosomal translocation involving IRF4 and the IgH locus, t(6;14)(p25;q32), may be associated with multiple myeloma. Alternatively spliced transcript variants have also been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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