Thermo Fisher Scientific Phospholamban Polyclonal Antibody
Phospholamban 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. 인간, 마우스, 랫트 시료에 반응. Affinity chromatography로 정제된 액상 항체로, PBS와 50% 글리세롤 용액에 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PLN (Accession P26678), corresponding to amino acid residues M1–C41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900388 |
Product Specific Information
Antibody detects endogenous levels of total Phospholamban.
Target Information
Phospholamban (PLB) is a 52 amino acid phosphoprotein that regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB forms an oligomer of five identical subunits, each containing a cytoplasmic and a transmembrane domain. The cytoplasmic domain (residues 1–25) includes phosphorylation sites and is highly basic and protease-sensitive, while the transmembrane domain (residues 25–52) is hydrophobic, protease-resistant, and stabilizes the pentamer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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