Thermo Fisher Scientific Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Monoclonal Antibody (SERPINA3/4190)
Alpha-1-Antichymotrypsin(SERPINA3) 단일클론 항체로, Histiocytoma 마커로 사용 가능. IHC(P) 및 IHC(PFA) 등 다양한 응용에 적합. 인간 시료 반응성, Mouse IgG2b(kappa) 아이소타입. Protein A/G 정제 및 4°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SERPINA3/4190 |
| Immunogen | Recombinant human Antichymotrypsin (AACT) protein fragment (around aa 49–187) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SERPINA encodes Alpha 1-ACT, an early-stage acute-phase plasma protein and serine protease inhibitor (serpin) that preferentially inactivates chymotrypsin, cathepsin G, and chymase.
Alpha-1-ACT is tightly associated with amyloid plaques in Alzheimer’s disease and in aged human and monkey brains. Regulation of serine proteases and their inhibitors plays an important role in neuromuscular differentiation.
Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed with Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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