Thermo Fisher Scientific IGF2BP3 Monoclonal Antibody (OTI7B10), TrueMAB
IGF2BP3 단백질을 인식하는 마우스 모노클론 항체로, Western Blot 및 IHC(Paraffin) 실험에 적합. 고순도 친화 크로마토그래피 정제. 액상 형태, 1 mg/mL 농도. 인간 시료 반응성, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7B10 |
| Immunogen | Full length human recombinant protein of human IGF2BP3 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family.
IMP-3 is expressed during embryogenesis and in certain malignancies. It is present in malignant melanoma but not in benign nevi, even when dysplastic features are present. IMP-3 expression is significantly higher in melanomas than in Spitz nevi and more pronounced in metastatic melanomas than in thin melanomas.
IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in regulating the biological behavior of this tumor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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