Thermo Fisher Scientific hnRNP D Polyclonal Antibody
Thermo Fisher Scientific의 hnRNP D Polyclonal Antibody는 인간 hnRNP D 단백질을 인식하는 토끼 유래 IgG 항체로, WB 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고농축 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA527533
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 18–225 of Human AUF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.69 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545009 |
Product Specific Information
- Recommended positive control: A431
- Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (82%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport.
While all hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm. The hnRNP D protein contains two quasi-RRM domains that bind RNA, localizing to both nucleus and cytoplasm, and plays a role in mRNA stability regulation. Alternative splicing produces four transcript variants.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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