Thermo Fisher Scientific hnRNP D Polyclonal Antibody
Western blot과 ICC/IF에 적합한 hnRNP D 폴리클로날 항체. 사람과 생쥐에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 용액으로 4°C 단기, -20°C 장기 보관 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA527534
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000–1:20,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 138–355 of Human AUF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545010 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain
- Predicted reactivity: Mouse (100%), Rat (98%), Chicken (98%), Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport. While all hnRNPs are present in the nucleus, some shuttle between the nucleus and cytoplasm. The encoded protein has two quasi-RRM domains that bind RNAs, localizes to both nucleus and cytoplasm, and is involved in mRNA stability regulation. Alternative splicing results in four transcript variants.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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