
Thermo Fisher Scientific SPAG4 Monoclonal Antibody (OTI3E9)
SPAG4 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 적합합니다. 인간 단백질에 반응하며, Mouse IgG2a 아이소타입입니다. 고순도의 액상 형태로, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 191–279 of SPAG4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725401 |
Target Information
The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece, and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail.
Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility.
In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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