Thermo Fisher Scientific MSH6 Monoclonal Antibody (UMAB258), UltraMAB
MSH6 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체입니다. IHC(P)에서 1:50 희석비로 검증되었으며, Human 시료에 반응합니다. Lyophilized 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB258 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–280 of human MSH6 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for detecting DNA damage and may promote apoptosis in normal cells, protecting mammals from UV-induced malignant transformation and contributing to skin cancer prevention.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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