Thermo Fisher Scientific BRD2 Monoclonal Antibody (12C2E4)
BRD2 단백질을 인식하는 Mouse Monoclonal Antibody (Clone 12C2E4). Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 인간 BRD2 단백질(675–725 aa 구간)을 면역원으로 제작. 연구용 전용 제품.
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Applications
- Western Blot (WB): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 12C2E4 |
| Immunogen | A region between residue 675 and 725 of human bromodomain containing 2 (BRD2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 6.8–7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a transcriptional regulator belonging to the BET (bromodomains and extra terminal domain) family of proteins. It associates with transcription complexes and acetylated chromatin during mitosis, selectively binding to acetylated lysine-12 of histone H4 via its two bromodomains.
The gene is located in the MHC class II region on chromosome 6p21.3 but is not directly involved in immune response. It has been implicated in juvenile myoclonic epilepsy, a common adolescent-onset epilepsy. Multiple alternatively spliced variants have been reported, though some full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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