Thermo Fisher Scientific BRD2 Monoclonal Antibody (12C2E4)
BRD2 단백질을 인식하는 Mouse monoclonal antibody (Clone 12C2E4). Western blot 및 Immunoprecipitation에 적합. Human에 반응하며 여러 포유류 종에서 예측 반응. 항원 친화 크로마토그래피로 정제된 액상형 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 20 µL/1 mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 12C2E4 |
| Immunogen | Region between residue 675 and 725 of human bromodomain containing 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 40 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, Bovine, Dog, Horse, Guinea pig, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, and Chinese hamster
Target Information
This gene encodes a transcriptional regulator belonging to the BET (bromodomains and extra terminal domain) family of proteins. It associates with transcription complexes and acetylated chromatin during mitosis, selectively binding to the acetylated lysine-12 residue of histone H4 through its two bromodomains.
The gene maps to the MHC class II region on chromosome 6p21.3 but is not involved in immune response. It has been implicated in juvenile myoclonic epilepsy. Multiple alternatively spliced variants have been described, though some full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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