Thermo Fisher Scientific hnRNP AB Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence:
  GAAAGAGGAT AAPPSGNQNG AEGDQINASK NEEDAGKMFV GGLSWDTSKK

• Storage recommendation:
  For short term use, store at 2–8°C up to 1 week.
  For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Predicted homology:
  Cow: 86%
  Dog: 86%
  Guinea Pig: 100%
  Human: 100%
  Mouse: 100%
  Rat: 93%

Target Information

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport.
While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties.
The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs.
Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(해당 제품의 항원 이미지 및 구조도)
PA5-113701_hnRNP_AB_Q99729-1_Rabbit_PDP.jpeg
PA5-113701_hnRNP_AB_Q99729-1_Rabbit.svg