Thermo Fisher Scientific ACCN4 Polyclonal Antibody
인간, 마우스, 랫트에 반응하는 ACCN4 폴리클로날 항체입니다. IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능합니다. KLH 결합 합성 펩타이드로부터 유래된 면역원으로 제작되었습니다. Protein A로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:300 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ACCN4/ASIC4, amino acids 451–539 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene belongs to the superfamily of acid-sensing ion channels (ASICs), which are proton-gated, amiloride-sensitive sodium channels. These channels are involved in synaptic transmission, pain perception, and mechanoperception.
The gene is predominantly expressed in the pituitary gland and was once considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, though no correlation was found between mutations in this gene and PDC.
Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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