Thermo Fisher Scientific ACCN2 Polyclonal Antibody
Thermo Fisher Scientific의 ACCN2 다클론 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ELISA에 적합하며, 고순도 Protein A 정제 항체입니다. KLH 접합 합성 펩타이드 유래 면역원으로 제작되었습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ACCN2/ASIC1, amino acids 332–460 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of this family are amiloride-sensitive sodium channels with intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop containing many cysteine residues with conserved spacing.
The encoded protein is expressed in most brain neurons and may function as an ion channel subunit. It is a cation channel with high affinity for sodium, gated by extracellular protons, and inhibited by amiloride. ASIC1 is permeable to Ca²⁺, Li⁺, and K⁺, and is expressed in dorsal root ganglia, sciatic nerves, olfactory bulb, cortical regions, hippocampal formation, amygdala, and cerebellum. Isoform 3 is expressed only in dorsal root ganglion, while isoform 1 is expressed in DRG, spinal cord, trigeminal ganglia, and trigeminal mesencephalic nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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