Thermo Fisher Scientific Phospho-ATF4 (Ser245) Polyclonal Antibody
Phospho-ATF4 (Ser245) 항체로 인간 ATF4 단백질의 인산화 부위를 특이적으로 인식합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Rabbit polyclonal 형식으로 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human ATF4 around the phosphorylation site of Ser245 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a transcription factor originally identified as a widely expressed mammalian DNA-binding protein that can bind a tax-responsive enhancer element in the LTR of HTLV-1. It was also characterized as the cAMP-response element binding protein 2 (CREB-2). The encoded protein belongs to a family of DNA-binding proteins, including AP-1 transcription factors, CREBs, and CREB-like proteins. These share a leucine zipper region for protein-protein interactions, located C-terminal to a basic DNA-binding domain. Two alternative transcripts encoding the same protein have been described, and two pseudogenes are located on the X chromosome at q28.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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