Thermo Fisher Scientific Sarcomeric Actinin Alpha 2/ACTN2 Recombinant Rabbit Monoclonal Antibody (ACTN2/7039R)
ACTN2 단백질을 인식하는 재조합 토끼 단클론 항체로, 면역조직화학 및 펩타이드 어레이 분석에 적합합니다. 인간 시료 반응성이 있으며, HEK293 세포에서 발현된 IgG 항체입니다. 보존제 없이 PBS 용액에 담긴 액상 형태로 제공됩니다.
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- 88-RBM6-P1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ACTN2/7039R |
| Immunogen | Recombinant fragment (aa 557–692) of human ACTN2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Alpha actinins belong to the spectrin gene superfamily, representing a diverse group of cytoskeletal proteins including alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in various cell types.
In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it binds actin to the membrane.
In skeletal, cardiac, and smooth muscle cells, alpha actinin isoforms localize to the Z-disc and dense bodies, anchoring myofibrillar actin filaments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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