Thermo Fisher Scientific ATG16L1 Polyclonal Antibody
ATG16L1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western Blot, ICC/IF, ELISA에 적용 가능. 인간 및 랫트 반응성. 동결건조 형태로 제공되며, 연구용으로만 사용.
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Thermo Fisher Scientific ATG16L1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:100 - 1:3000 | View 1 publication |
| ELISA | 1:2000 - 1:3000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal residues of human ATG16L1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1070450 |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material. After reconstitution, store aliquots at -20°C for higher stability, or at 4°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
Target Information
Autophagy related protein 16L (ATG16L1) is encoded by the ATG16L gene located on chromosome 2 in humans. Also known as WD30 or IBD10 (Inflammatory Bowel Disease 10).
ATG12 and ATG5 conjugate with each other and oligomerize with ATG16L to form an 800 kDa Atg16L complex. This complex facilitates coupling or lipidation of LC3 to phosphatidylethanolamine (PE), serving as a key marker for autophagy.
The ATG16L complex, along with ATG18 and ATG21, prevents premature cleavage of ATG8-PE by cysteine protease Atg4 until autophagosome completion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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