
Thermo Fisher Scientific Influenza A M2 Polyclonal Antibody
Influenza A 바이러스 M2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 ICC/IF에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제. 연구용으로만 사용 가능하며, 장기 보관 시 -20°C에서 유지.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | View 3 publications |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 1 publication |
| In vitro Assay (IV) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Published Species | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment of influenza A virus M2 (A/Puerto Rico/8/1934(H1N1)) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.61 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549706 |
Product Specific Information
- Recommended positive controls: Influenza virus (A/WSN/1933(H1N1))-infected DF-1 cell lysates, H1N1-infected H1299
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Influenza A virus is an enveloped virus encoding 10 polypeptides. RNA segment 7 encodes two proteins: M1 (matrix 1) and M2 (matrix 2).
M1 protein is encoded by an mRNA that is colinear, while M2 protein is synthesized from spliced mRNA.
M2 protein is a transmembrane protein composed of three domains:
- 24 residues representing the N-terminal region
- 19 hydrophobic residues serving as a membrane anchor
- 54 residues near the C-terminal in the cytoplasmic domain
The M2 protein plays a role in influenza replication and assembly of virion particles. It functions as an acid-activated ion channel essential for virus replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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