Thermo Fisher Scientific ITPR3 Polyclonal Antibody
ITPR3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합. 인간 및 생쥐 반응성. 고순도 Affinity Chromatography 정제 및 안정적인 PBS/glycerol 저장용액 제공.
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Thermo Fisher Scientific ITPR3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1630–1870 of human ITPR3 (NP_0022152) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.59 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805108 |
Product Specific Information
Immunogen sequence:
EGSEAYQRCE SGGFLSKLIQ HTKDLMESEE KLCIKVLRTL QQMLLKKTKY GDRGNQLRKM LLQNYLQNRK STSRGDLPDP IGTGLDPDWS AIAATQCRLD KEGATKLVCD LITSTKNEKI FQESIGLAIH LLDGGNTEIQ KSFHNLMMSD KKSERFFKVL HDRMKRAQQE TKSTVAVNMN DLGSQPHEDR EPVDPTTKGR VASFSIPGSS SRYSLGPSLR RGHEVSERVQ SSEMGTSVLI M
Positive Samples: HeLa, LO2, HepG2
Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein
Target Information
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-88758_ITPR3_Q14573-1_Rabbit.svg, PA5-88758_ITPR3_Q14573-1_Rabbit_PDP.jpeg)
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