
Thermo Fisher Scientific RAB7A Polyclonal Antibody
RAB7A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, ELISA, IP에 적합하며, PBS/glycerol buffer에 보관됩니다. Affinity chromatography로 정제된 고품질 연구용 항체입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 200 µg–400 µg extracts |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100–207 of human RAB7 (NP_004628.4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.56 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805106 |
Product Specific Information
- Positive Samples: A-431, HeLa, Mouse brain, Rat brain
- Cellular Location: Cytoplasmic side, Cytoplasmic vesicle, Late endosome membrane, Lipid droplet, Lysosome membrane, Melanosome membrane, Peripheral membrane protein, Autophagosome membrane, Phagosome membrane
- Immunogen Sequence:
DSWRDEFLIQ ASPRDPENFP FVVLGNKIDL ENRQVATKRA QAWCYSKNNI PYFETSAKEA INVEQAFQTI ARNALKQETE VELYNEFPEP IKLDKNDRAK ASAESCSC
Target Information
RAB family members are small, RAS-related GTP-binding proteins that are key regulators of vesicular transport. Each RAB protein interacts with multiple proteins involved in exocytic and endocytic pathways.
RAB7 regulates vesicle traffic in the late endosomes and from late endosomes to lysosomes. It also participates in cellular vacuolation induced by the VacA cytotoxin of Helicobacter pylori.
Mutations in conserved residues of this gene are associated with Charcot-Marie-Tooth (CMT) type 2 neuropathies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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