Thermo Fisher Scientific Phospho-EED (Thr55) Polyclonal Antibody
EED 단백질의 Thr55 인산화 상태를 특이적으로 인식하는 폴리클로날 항체입니다. Human, Mouse, Rat 시료에 반응하며 WB, IHC, ICC/IF에 사용 가능합니다. 고순도 정제 및 액상 형태로 제공되며, -20°C에서 안정적으로 보관됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Phospho-EED (Thr55) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EED (Accession O75530), corresponding to amino acid residues around phosphorylated Thr55 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816761 |
Product Specific Information
Antibody detects endogenous levels of EED only when phosphorylated at Thr55.
Target Information
The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins.
The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression.
EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin Beta-7 subunit.
EED exerts antiviral activity at the late stage of HIV-1 replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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