Thermo Fisher Scientific Phospho-INCENP (Thr59) Polyclonal Antibody
Phospho-INCENP (Thr59) 폴리클로날 항체로, 인간·마우스·랫트 시료에서 인산화된 INCENP를 검출. Western blot, IHC, ICC/IF에 적합. 고순도 정제, 1 mg/mL 농도, PBS/glycerol buffer 보존. 연구용 전용 제품.
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Thermo Fisher Scientific Phospho-INCENP (Thr59) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human INCENP (Accession Q9NQS7), corresponding to amino acid residues around phosphorylated Thr59 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817581 |
Product Specific Information
Antibody detects endogenous levels of INCENP only when phosphorylated at Thr59.
Target Information
Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis.
INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex, highly basic, multidomain protein that dynamically translocates from metaphase chromosomes to the spindle midzone during or just prior to anaphase.
Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow and is ultimately discarded in the midbody at the completion of cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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