Thermo Fisher Scientific NCK2 Polyclonal Antibody, MaxPab
NCK2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합. Human 종에 반응하며 Mouse/IgG 호스트 사용. 친화 크로마토그래피로 정제된 액상 형태로, PBS(pH 7.4)에 보존제 없이 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- H00008440-B01P
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific NCK2 Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB): Tested dilution 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NCK2 (NP_001004720.1, 1–380 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MTEEVIVIAK WDYTAQQDQE LDIKKNERLW LLDDSKTWWR VRNAANRTGY VPSNYVERKN SLKKGSLVKN LKDTLGLGKT RRKTSARDAS PTPSTDAEYP ANGSGADRIY DLNIPAFVKF AYVAEREDEL SLVKGSRVTV MEKCSDGWWR GSYNGQIGWF PSNYVLEEVD EAAAESPSFL SLRKGASLSN GQGSRVLHVV QTLYPFSSVT EEELNFEKGE TMEVIEKPEN DPEWWKCKNA RGQVGLVPKN YVVVLSDGPA LHPAHAPQIS YTGPSSSGRF AGREWYYGNV TRHQAECALN ERGVEGDFLI RDSESSPSDF SVSLKASGKN KHFKVQLVDN VYCIGQRRFH TMDELVEHYK KAPIFTSEHG EKLYLVRALQ
Target Information
The NCK family of SH2/SH3 adaptor proteins consists of two members, NCK1 and NCK2, which couple tyrosine kinase signaling—including the EGF and PDGF receptor pathways—to downstream signaling proteins.
NCK2 binds human PDGFR-b (Tyr-1009); overexpression of NCK2 inhibits PDGF-induced membrane ruffling and lamellipod formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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