Thermo Fisher Scientific EEA1 Monoclonal Antibody (1D4)
EEA1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 1D4). Western blot 및 ELISA에 적합하며, 인간, 마우스, 랫트 시료에 반응. 액상 형태로 제공되며, -20°C에서 보관. 연구용 전용.
- 카탈로그번호
- H00008411-M02A
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific EEA1 Monoclonal Antibody (1D4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D4 |
| Immunogen | EEA1 (NP_003557, 1312 a.a. ~1411 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KVLELQRKLD NTTAAVQELG RENQSLQIKH TQALNRKWAE DNEVQNCMAC GKGFSVTVRR HHCRQCGNIF CAECSAKNAL TPSSKKPVRV CDACFNDLQG
Target Information
Early endosomal antigen 1 (EEA1) is a 162 kDa membrane-bound protein specific to the early endosome and essential for fusion between early endocytic vesicles. Early endosomes are cytoplasmic compartments that fuse with endocytic vesicles for redistribution of extracellular compounds.
Zinc-finger-like domains are present in both amino and carboxyl-terminal regions of EEA1, with the carboxyl-terminal domain being a conserved zinc-binding region crucial for intracellular localization. Membrane association of EEA1 depends on phosphatidyl 3-kinase activity; inhibitors cause EEA1 to dissociate from early endosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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