Thermo Fisher Scientific Cyclin B3 Polyclonal Antibody
Cyclin B3 단백질을 검출하는 Thermo Fisher의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 세포 주기 조절 연구용.
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Thermo Fisher Scientific Cyclin B3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Cyclin B3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2553982 |
Product Specific Information
- Detects endogenous Cyclin B3 protein at a molecular weight of 158 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Cell proliferation is controlled at specific stages of the cell cycle by distinct protein kinase complexes, consisting of catalytic and regulatory subunits. Cyclins (A, B, C, D, E, F, G, H, I, K, L, T) and related proteins such as Dbf4 act as regulatory subunits.
Cyclin B3 (CCNB3, CYCB3) is a 1,395 amino acid nuclear protein belonging to the cyclin family. It is highly expressed in testis and plays a crucial role in early meiotic prophase I, important for meiotic cell cycle regulation. Three isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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